Principal Investigator, Children's National Medical Center
Joshua Corbin is a Principal Investigator at the Center for Neuroscience Research at Children’s National Medical Center with academic appointment as Associate Professor of Pediatrics, Pharmacology and Physiology at George Washington University’s School of Medicine and Health Sciences. He holds a B.A. from Rutgers University and Ph.D. in neuroscience from the University of North Carolina Chapel Hill. He carried out his post doctoral work at the Skirball Institute at the NYU School of Medicine. Dr. Corbin started his own in lab in 2004 in department of Neuroscience at Georgetown University, and in 2006 moved to the Center for Neuroscience Research at Children’s National Medical Center. The Corbin lab is currently funded by the NIH and has received previous grants from Autism Speaks and the Fragile Foundation, FRAXA. He also currently serves as a consultant for public and private organizations focused on understanding and treating a variety of neurodevelopmental disorders and has served as a panel reviewer for the NIH, NSF, Autism Speaks and Department of Defense. He also had the pleasure of presenting his work to Prince Philip, Duke of Edinburgh during the Royal visit to the US in 2007.
How brain circuitry regulating specific behaviors emerges from development remains unknown. Research in our laboratory is directed toward addressing how genetic embryonic neurodevelopmental programs pattern development of circuitry of the limbic system: an interconnected set of brain structures that includes the olfactory system, amygdala, and hypothalamus. Moreover, we are interested in the consequences of when these processes go awry, resulting in neurodevelopmental disorders such as autism spectrum disorders.
To address these questions, using a murine model, we employ a variety of state-of-the-art techniques, such as conditional transgenic and optogenetic approaches. From these studies we hope not only to gain greater insight into the neurotypical developing brain, but address core behavioral deficits in prevalent human neurodevelopmental disorders.
Neuroscience and Cognitive Science