My current and future research interests are in the fields of developmental neuroscience and in nervous system injury and disease. My laboratory uses an integrated, multidisciplinary approach that includes molecular biology and genetics, cellular neurobiology, electrophysiology and neurobehavior. We are interested in defining the cellular and molecular mechanisms underlying the impact of neonatal injury and genetic disorders on brain development and function. We focus on white matter and cerebellum, where we study neurogenesis and gliogenesis, oligodendrocyte development and myelination, glial signaling and neural circuits. We are combining experiments performed in different types of neural cell cultures with studies performed in transgenic mice in vivo and in human post-mortem tissue.